Minimum local analgesic concentration of extradural bupivacaine increases with progression of labour
نویسندگان
چکیده
منابع مشابه
Extradural methadone and bupivacaine in labour.
We performed a double-blind placebo-controlled study of the effects of extradural administration of methadone 5 mg or saline, followed by bupivacaine, in 42 women in early labour. Motor block and pain scores were significantly less in the methadone group. The requirement for bupivacaine also was reduced by methadone, but this was not statistically significant. There were no troublesome side eff...
متن کاملCardiovascular changes in labour associated with extradural analgesia using bupivacaine.
Cardiovascular changes were monitored continuously in 13 women during stimulated labour conducted under extradural analgesia with bupivacaine. Three solutions of bupivacaine (0.5% plain, 0.25% with adrenaline and 0.5% with adrenaline) were administered in a random fashion. The results show that the plain solution of bupivacaine was associated with a decrease in central venous pressure and an in...
متن کاملComparison of bupivacaine and bupivacaine with fentanyl in continuous extradural analgesia during labour.
In a randomized, double-blind study of 39 mothers in labour, we have compared a loading dose of 0.5% bupivacaine 6.0 ml and fentanyl 100 micrograms given extradurally, followed by an infusion of 0.08% bupivacaine 15 ml h-1 plus fentanyl 37.5 micrograms h-1, with a loading dose of 0.5% bupivacaine 6.0 ml and saline 2.0 ml, followed by an extradural infusion of 0.08% bupivacaine alone, per hour. ...
متن کاملIntermittent vs continuous extradural infusion of bupivacaine during labour.
Sir,—The absolute significance of the findings of Eddleston and colleagues [1] would have been much clearer if they had compared the two extradural groups with a control group which did not receive extradural bupivacainc. Although this control group would have been self-selected and not subject to randomization, the group could have been matched as closely as possible to the two study groups. I...
متن کاملEffect of intravenous versus epidural fentanyl on the minimum local analgesic concentration of epidural bupivacaine in labor.
BACKGROUND The minimum local analgesic concentration (MLAC) has been defined as the median effective local analgesic concentration (EC50) in a 20-ml volume for epidural analgesia in the first stage of labor. The aim of this study was to determine the relative local anesthetic sparing efficacies of intravenous and epidural fentanyl by comparison of their effects on the MLAC of bupivacaine. MET...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1998
ISSN: 0007-0912
DOI: 10.1093/bja/80.1.11